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Key Reactions
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We have done most kinds of reactions successfully, including traditional and new-appearing reactions. The following examples are some of which we are quite familiar with or have been done in commercial lot frequently. |
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| 2. Heterocyclics Synthesis |
| 2.1. Fischer Indole Synthesis |
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| 2.2. Imidazole Synthesis |
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| 2.3. Indazole synthesis |
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| 2.4. Quinoline synthesis |
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| 2.5. Thiazole synthesis |
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| 2.6. Oxazole synthesis |
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| 3. Reduction Reactions |
| 3.1. Reduction with Lithium Aluminum Hydride |
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| 3.2. Reduction with Borohydride |
| 3.2.1 Sodium Borohydride |
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| 3.2.2 Zinc Borohydride |
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| 3.2.3 Sodium Cyanoborohydride |
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| 3.3 Reduction with Diisobutylaluminum Hydride |
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| 3.4 Catalytic Hydrogenation |
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| 3.5 Reduction with Hydrazine (Wolff-Kishner) |
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| 4. Oxidation Reactions |
| 4.1 Oxidation with Chromium (VI) |
| 4.1.1 Collins oxidation |
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| 4.1.2 PCC reagent |
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| 4.2 Dimethyl Sulfoxide Oxidations |
| 4.2.1 Dimethyl Sulfoxide - Acetic Anhydride reagent |
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| 4.2.2 Swern Oxidation |
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| 4.3 Oxidation with Manganese Dioxide |
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| 4.4 Dess-Martin Periodinane Oxidation |
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| 4.5 mCBPA reagent |
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| 4.6 Oxidation with Permanganate |
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| 5. Suzuki Coupling |
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| 6. Heck-Fujiwara Coupling |
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| 7. Grignard Reactions |
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| 8. Dies-Alder Reactions |
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| 9. Esterification and Ester Change Reaction |
| 9.1 Esterification |
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| 9.2 Ester Change reaction |
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| 10. Chiral Reactions |
- Kinetic resolution with D-TA and DDA
- Chiral ligand-supported hydrogenation
- Auxiliary-assistant synthesis
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